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Healthcare's agent bottleneck is human incentives, not model capability

Tener CEO Trey Holterman argues that AI agents can now handle healthcare's referral paperwork, but patient behavior, misaligned incentives and chatbot-driven specialty demand remain harder problems than the technology.

Trey HoltermanTenerChenMedHealthcare AIAgentic AI
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Healthcare's agent bottleneck is human incentives, not model capability

Recorded 4 October 2026 · 26 min

Trey Holterman, CEO of Tener, argues that the binding constraint on healthcare AI is no longer model capability but human behavior and incentives. Tener's agents match complex insurance guidelines against patient histories, which he gives as 400 pages in his example, across a network of more than 430,000 referring providers. Even so, he rates getting patients and referral sources to act as "difficulty 10 out of 10."

Recorded live at the New York Stock Exchange with host Sophia, the conversation turns on a tension. Holterman is bullish that agents can clear referral backlogs. He also expects chatbots to push more patients toward specialists, and he argues that almost any incentive structure can be gamed. His figures come from a vendor with stated growth targets, not from independent data.

  1. Agentic means chained judgment — ▶ 1:00

    Holterman defines agentic work not as simple automation but as multiple steps of nondeterministic reasoning tied together toward an end outcome. Getting a patient onto a complex therapy, a device or even a first appointment involves a series of steps, each needing judgment, thinking and tool use. Tener's approach was to put that process on rails. He relays that an early investor said in 2024 that Tener was the first agentic healthcare application running at scale. That is an investor's characterization, not an independently established fact.

  2. Agents work behind the patient — ▶ 4:06

    Technology, Holterman says, moves far faster than consumer behavior. Tener's average patient is a 67-year-old woman in the Midwest who is delighted by a call that knows the next step in her journey and is probably not using consumer agents herself. Tener handles the coordination behind the scenes and texts or calls her only when she must act. Because every action must be tightly controlled, he does not expect providers to deploy fully rogue personal-assistant concierges soon. He expects them to adopt the technology selectively.

  3. Reading is solved; people are not — ▶ 5:25

    The first blocker is matching a complex corpus of insurance guidelines against a 400-page medical history to decide whether a provider can take a patient. Holterman calls it made for language models. Tasks once pre-codified, such as chasing missing referral documentation, calling payers or coordinating benefits across three payers, can now run as long-running agents. The hard parts are integration in a non-integrated environment, escalation rails to clinicians and administrators, and the behavior of payers and patients. Referral sources are not always incentivized to follow up, and patients have a million things going on.

  4. EMR subsidies distorted adoption — ▶ 8:51

    In what he calls a hot take, Holterman blames healthcare's reputation as a technology laggard on government money. About 20 years ago, funds were paid to providers to adopt EMR software. They were paid to buy expensive software, not because paper was hurting them. He says this produced an unnatural adoption cycle, a bifurcated long-tail market, poor products and miserable workflows. Tools that work on top of those systems and deliver a 10x better experience, he argues, move even difficult procurement cycles. This is his interpretation, and the transcript offers no supporting data.

  5. Any incentive can be gamed — ▶ 14:41

    Holterman says nearly every incentive scheme gets gamed. He cites states handing Medicaid patients to large payers and says more than 50% of patients have moved from Medicare to Medicare Advantage; the passage blends the two programs. In his hypothetical, a payer prepaid $20 billion to manage a state's plan would approve claims until it reaches what it was paid to dispense, then deny. His counterexample is ChenMed in Florida, which does not earn more from extra treatments but wants patients to stay healthy. He would fund primary care much more aggressively than the current five minutes per patient allows.

  6. Chatbots may swamp specialists — ▶ 17:30

    Holterman predicts that many healthcare inquiries will run through chatbots, which he considers trigger-happy about referrals. In his downside scenario, a 3-month wait to see a rheumatologist stretches to 5 months, and low-acuity visits displace urgent ones. He notes that overburdened medical assistants and coordinators already struggle to tell high-acuity patients from someone seeking a fourth opinion after reading something online. His bet is that provider-side models will triage effectively and that telehealth will absorb patients who need only a specialized opinion. The forecast is a prediction and comes with no supporting data.

  7. Scale targets and K-shaped market — ▶ 20:47

    Tener has about 300 people in New York and processes patients for about one in five providers. It wants to reach about 50%. Holterman cites an Arizona group where patients went 30 days without contact and says the status quo is 18 to 21 days. He wants oncology referrals contacted the same day within 12 to 18 months. He expects a more K-shaped, consolidated market in a year. In 10 years he expects real-time patient flow, like an order exchange where nobody wonders whether a trade will confirm in 4 days or 40.

The open question. Can agents make referral follow-up reliable when the obstacle, in Holterman's own telling, is that referral sources and patients lack the incentive to act? Tener offers targets, not outcome data: from one in five providers to about 50%, and from an 18 to 21 day status quo to same-day contact. It is also unclear whether a chatbot-driven surge in specialty demand can be absorbed by the triage tools he expects providers to adopt.

Watch the full video at https://www.youtube.com/watch?v=sCBeRJlxT6w.

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